219671-80-4

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-Cyanopyridin-3-yl)benzoic acid is used as a chemical intermediate for the development of new drugs. Its unique structure allows it to be a component in the synthesis of pharmaceutical compounds, contributing to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(2-Cyanopyridin-3-yl)benzoic acid is utilized in the production of crop protection chemicals. It plays a crucial role in the synthesis of compounds that help protect crops from pests and diseases, thereby enhancing agricultural productivity.
Used in Chemical Synthesis:
4-(2-Cyanopyridin-3-yl)benzoic acid is employed as a key intermediate in chemical synthesis processes. Its presence in the synthesis of various organic compounds highlights its versatility and importance in the field of organic chemistry.
Used in Research:
4-(2-Cyanopyridin-3-yl)benzoic acid is also used in research settings to explore its properties and potential applications further. Its unique structure provides a foundation for investigating new chemical reactions and the development of innovative materials and compounds.

Upstream product

• 456-22-4 4-Fluorobenzoic acid 
• 13472-85-0 2-methoxy-5-bromopyridine 
• 14047-29-1 4-carboxyphenylboronic acid 
• 497-19-8 sodium carbonate 
• 219672-73-8 4-(6-methoxy-pyridin-3-yl)-benzoic acid ethyl ester 

Downstream Products

• 1103458-56-5 N-[3-(4,5-dichloro-6-oxo-6H-pyridazin-1-ylmethyl)-2-methylphenyl]-4-(6-methoxy-pyridin-3-yl)-benzamide 
• 340040-83-7 3-(2-{1-[4-(6-Methoxy-pyridin-3-yl)-benzoyl]-pyrrolidin-2-(R,S)-yl}-ethyl)-benzonitrile 
• 370863-96-0 3-{1-[4-(6-Methoxypyridin-3-yl)benzoyl]-piperidin-4-yl}benzamidine trifluoroacetate 
• 370863-86-8 3-{1-[4-(6-Methoxypyridin-3-yl)benzoyl]-1,2,3,6-tetrahydropyridin-4-yl]-benzamidine trifluoroacetate 
• 340040-87-1 4-(6-Oxo-1,6-dihydro-pyridin-3-yl)-benzoic acid 

Relevant academic research and scientific papers

A general palladium-catalyzed cross-coupling of aryl fluorides and organotitanium (IV) reagents

Pd(OAc)2/1-[2-(di-tert-butylphosphanyl)phenyl]-4-methoxy-piperidine was demonstrated to effectively catalyze cross-coupling of aryl fluoride and aryl(alkyl) titanium reagent. Both electron-deficient and electron-rich aryl fluoride can react effectively with nucleophile and provide extensive functional groups tolerance. 2-Arylated product was realized by selective activation of the C–F bond. Graphic abstract: [Figure not available: see fulltext.].

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43)

The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases.

SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL) BENZOHETEROARYL COMPOUNDS

This invention is directed to an (aminoiminomethyl or aminomethyl) benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.

1-aroyl-piperidinyl benzamidines

This invention relates to compounds of formula which inhibit Factor Xa or tryptase, to pharmaceutical compositions containing the compounds, and to the use of the compounds for the treatment of patients suffering from conditions which can be ameliorated by the administration of an inhibitor of Factor Xa or tryptase.

N-acylsulfonamide apoptosis promoters

N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.

N-Acylsulfonamide apoptosis promoters

N-Benzoyl arylsulfonamides having the formula Are BCL-X1 inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-X1 inhibiting compositions and methods of promoting apoptosis in a mammal.