1103519-64-7

Basic information

• Product Name: C₁₈H₁₇NO₆
• CAS NO: 1103519-64-7
• Molecular Weight: 343.336
• Mol File: 1103519-64-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₇NO₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₇NO₆(1103519-64-7)
• EPA Substance Registry System: C₁₈H₁₇NO₆(1103519-64-7)

Safety Data

• Hazardous Substances Data: 1103519-64-7(Hazardous Substances Data)

Upstream product

• 2450-26-2 2-nitrovanillin 
• 848598-50-5 malonic acid monophenethyl ester 

Relevant articles and documents

Synthesis of trans-caffeate analogues and their bioactivities against HIV-1 integrase and cancer cell lines

Forty caffeate analogues were synthesized via a convenient method starting from vanillin with moderate to good yields. The testing of biological activity of these compounds against HIV-1 integrase indicates that four compounds: bornyl caffeate, bornyl 2-nitrocaffeate, 5-nitrocaffeic acid and 5-nitrocaffeic acid phenethyl ester (5-nitroCAPE) possess a good HIV integrase inhibitory activity, IC50 19.9, 26.8, 25.0 and 13.5 μM, respectively. Twelve caffeate analogues were tested by MTT assay on growth of human hepatocellular carcinoma BEL-7404, human breast MCF-7 adenocarcinoma, human lung A549 adenocarcinoma and human gastric cancer BCG823 cell lines, respectively. And the best result is IC50 5.5 μM for CAPE against BEL-7404.