110372-54-8Relevant academic research and scientific papers
Synthesis of Optically Active Substituted Cyclohexenones from Carbohydrates by Catalytic Ferrier Rearrangement
Chida, Noritaka,Ohtsuka, Masami,Ogura, Katsuyuki,Ogawa, Seiichiro
, p. 2118 - 2121 (2007/10/02)
Conversion of hex-5-enopyranosides into substituted cyclohexenones (Ferrier rearrangement) was found to proceed efficiently with a catalytic amount of various mercury(II) salts at room temperature in a neutral solvent system.Among the mercury(II) salts tested, mercury(II) trifluoroacetate showed the highest activity.Four optically active cyclohexenones were prepared from hex-5-enopyranosides utilizing this method.
Total Synthesis of Antibiotic Hygromycin A
Chida, Noritaka,Ohtsuka, Masami,Nakazawa, Keiichi,Ogawa, Seiichiro
, p. 2976 - 2983 (2007/10/02)
The first total synthesis of the antibiotic (-)-hygromycin A (1) has been achieved by a coupling reaction of the sugar moiety (2) and the cyclitol moiety (3).Both components were synthesized in homochiral forms starting from D-glucose.This synthesis fully
α-Glucosidase Inhibitors, 5.- Investigations towards a Synthesis of C1-Branched Cyclitols from D-Glucose
Koehn, Arnim,Schmidt, Richard R.
, p. 1045 - 1054 (2007/10/02)
The glucose derivatives 1 and 2 were transformed by Ferrier rearrangement as one of the reaction steps into the cyclitol derivatives 3a,b and 4a,b, respectively.The attachment of a functional C1-side chain at the carbonyl group was tested with
