110392-87-5Relevant academic research and scientific papers
"Furan endwise peeling" of celluloses: Mechanistic studies and application perspectives of a novel reaction
Yoneda, Yuko,Krainz, Karin,Liebner, Falk,Potthast, Antje,Rosenau, Thomas,Karakawa, Makoto,Nakatsubo, Fumiaki
, p. 475 - 484 (2008)
The mechanism of a novel reaction type, the "furan endwise peeling" reaction, has been studied. Making extensive use of experiments on model compounds, the structural prerequisites to the reaction were found to be a 2-hydroxpyran β-glycosidically linked t
Synthesis and biological evaluation of modified 2-deoxystreptamine dimers
Coste, Gerald,Horlacher, Tim,Molina, Lidia,Moreno-Vargas, Antonio J.,Carmona, Ana T.,Robina, Inmaculada,Seeberger, Peter H.,Gerber-Lemaire, Sandrine
experimental part, p. 1759 - 1770 (2011/07/30)
Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for analogues with better pharmacological profiles. The synthesis of 2-deoxystreptamine (2-DOS) dimers linked by polyamines and analogues based on furylcarbopeptoid skeletons is described. Potent and selective ligands for bacterial 16S rRNA were identified using microarray techniques by determining the affinity of these derivatives toward bacterial and human ribosomal RNAs. Georg Thieme Verlag Stuttgart - New York.
