1104076-06-3Relevant academic research and scientific papers
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines
Schenone, Silvia,Brullo, Chiara,Bruno, Olga,Bondavalli, Francesco,Mosti, Luisa,Maga, Giovanni,Crespan, Emmanuele,Carraro, Fabio,Manetti, Fabrizio,Tintori, Cristina,Botta, Maurizio
experimental part, p. 2665 - 2676 (2009/04/11)
The synthesis of new 4-amino substituted pyrazolo[3,4-d]pyrimidines along with their activity in cell-free enzymatic assays on Src and Abl tyrosine kinases is reported. Some compounds emerged as good dual inhibitors of the two enzymes, showed antiprolifer
