1104077-77-1Relevant academic research and scientific papers
Practical enantioselective synthesis of a 3-aryl-3-trifluoromethyl-2- aminopropanol derivative
Alimardanov, Asaf,Nikitenko, Antonia,Connolly, Terrence J.,Feigelson, Gregg,Chan, Anita W.,Ding, Zhixian,Ghosh, Mousumi,Shi, Xinxu,Ren, Jianxin,Hansen, Eric,Farr, Roger,MacEwan, Michael,Tadayon, Sam,Springer, Dane M.,Kreft, Anthony F.,Ho, Douglas M.,Potoski, John R.
experimental part, p. 1161 - 1168 (2010/04/22)
Development of a large-scale enantioselective synthesis of a lead compound containing a 3-aryl-3-trifluoromethyl-2-aminopropanol core is described. A single isomer of 3,3-disubstituted acrylic acid derivative was prepared via Perkin condensation or Horner
PROCESS FOR THE PREPARATION OF TRIFLUOROALKYL-PHENYL AND HETEROCYCLIC SULFONAMIDES
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Page/Page column 14, (2009/02/11)
A novel trifluoroacetylating agent, i.e., N-trifluoroacetylmorpholine, is described. This reagent is useful in the preparation of phenyl and heterocyclic sulfonamide compounds. Methods are therefore described for preparing sulfonamide compounds of the fol
PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF HETEROCYCLIC SULFONAMIDE COMPOUNDS
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Page/Page column 23-24, (2009/02/11)
Methods for preparing compound of formula (I) are described, wherein R1-R3 are defined herein, as are methods for preparing the intermediates formed therein. Also described are methods for enantioselectively preparing a chiral compou
