1104502-47-7Relevant academic research and scientific papers
Exploration of diverse hinge-binding scaffolds for selective Aurora kinase inhibitors
Ji, Zhiqin,Dai, Yujia,Abad-Zapatero, Cele,Albert, Daniel H.,Bouska, Jennifer J.,Glaser, Keith B.,Marcotte, Patrick A.,Soni, Nirupama B.,Magoc, Terry J.,Stewart, Kent D.,Wei, Ru-Qi,Davidsen, Steve K.,Michaelides, Michael R.
, p. 4528 - 4531 (2012/08/08)
Four hinge-binding scaffolds have been explored for novel selective Aurora kinase inhibitors. The structure activity relationship, selectivity and pharmacokinetic profiles have been evaluated.
INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AS INHIBITORS OF PROTEIN KINASES
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Page/Page column 48, (2009/03/07)
Compounds that inhibit Aurora-kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
