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[1-[2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl]-3-N-[3-N'-(4-azidosalicylyl)aminopropyl]thymine]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1104731-83-0

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1104731-83-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1104731-83-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,4,7,3 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1104731-83:
(9*1)+(8*1)+(7*0)+(6*4)+(5*7)+(4*3)+(3*1)+(2*8)+(1*3)=110
110 % 10 = 0
So 1104731-83-0 is a valid CAS Registry Number.

1104731-83-0Downstream Products

1104731-83-0Relevant academic research and scientific papers

Novel N-3 substituted TSAO-T derivatives: Synthesis and anti-HIV-evaluation

Bonache, Maria-Cruz,Quesada, Ernesto,Sheen, Chih-Wei,Balzarini, Jan,Sluis-Cremer, Nicolas,Perez-Perez, Maria Jesus,Camarasa, Maria-Jose,San-Felix, Ana

, p. 351 - 367 (2008/09/20)

Novel derivatives of the anti-HIV-1 agent, TSAO-T, bearing at the N-3 position alkylating groups or photoaffinity labels were prepared and evaluated for their anti-HIV activity. All of these compounds demonstrated pronounced anti-HIV-1 activity and inhibited HIV-1 RT; however, we were unable to detect stable covalent linkages between inhibitor and enzyme. In addition, compounds with an alcohol functional group connected to the N-3 position through a cis or trans double bond have been prepared. These compounds have been useful to study how the conformational restriction of the linker affects in the interaction between the N-3 substituent and the HIV-1 RT enzyme. Copyright Taylor & Francis Group, LLC.

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