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2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine is an adenosine derivative that plays a crucial role in the synthesis of DNA. It is characterized by its unique chemical structure, which includes a 2'-deoxyribose sugar, a 5'-O-dimethoxytrityl (DMT) group, and a phenoxyacetyl group attached to the N6 position of the adenine base. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine is essential for the preparation of synthetic DNA molecules, particularly those designed for specific applications such as membrane-insertable amphiphilic DNA.

110522-82-2

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110522-82-2 Usage

Uses

Used in Synthetic DNA Preparation:
2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine is used as a key building block in the synthesis of synthetic DNA molecules. Its unique structure allows for the efficient incorporation of various functional groups and modifications, enabling the creation of DNA sequences with specific properties and functions.
Used in Membrane-Insertable Amphiphilic DNA:
In the field of membrane biology, 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine is used as a component in the design and synthesis of membrane-insertable amphiphilic DNA. These DNA molecules have the ability to interact with and integrate into lipid bilayers, making them valuable tools for studying membrane-associated processes and developing novel biomaterials and drug delivery systems.
Used in Pharmaceutical and Biomedical Research:
Due to its unique chemical properties and potential for modification, 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine is also used in pharmaceutical and biomedical research. It can be employed as a starting material for the development of new drugs, diagnostic tools, and therapeutic agents, particularly those targeting nucleic acid-based mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 110522-82-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,5,2 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 110522-82:
(8*1)+(7*1)+(6*0)+(5*5)+(4*2)+(3*2)+(2*8)+(1*2)=72
72 % 10 = 2
So 110522-82-2 is a valid CAS Registry Number.

110522-82-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine

1.2 Other means of identification

Product number -
Other names D'-Methoxy-diglykolaldehyd

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:110522-82-2 SDS

110522-82-2Relevant academic research and scientific papers

FACILE REMOVAL OF NEW BASE PROTECTING GROUPS USEFUL IN OLIGONUCLEOTIDE SYNTHESIS

Schulhof, J. C.,Molko, D.,Teoule, R.

, p. 51 - 54 (2007/10/02)

New base protecting groups are proposed in place of benzoyl and isobutyryl groups.They are phenoxy acetyl for adenine and guanine and isobutyryl for cytosine.They are cleaved in aqueous ammonia in a shorter time at lower temperature.These easily removable groups are useful in the synthesis of modified oligonucleotides, containing fragile bases.

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