110547-58-5Relevant academic research and scientific papers
Photoinduced Nickel-Catalyzed Chemo- and Regioselective Hydroalkylation of Internal Alkynes with Ether and Amide α-Hetero C(sp3)-H Bonds
Deng, Hong-Ping,Fan, Xuan-Zi,Chen, Zhi-Hui,Xu, Qing-Hua,Wu, Jie
, p. 13579 - 13584 (2017)
A direct hydroalkylation of disubstituted alkynes with unfunctionalized ethers and amides was achieved in an atom-efficient and additive-free manner through the synergistic combination of photoredox and nickel catalysis. The protocol was effective with a wide range of internal alkynes, providing products in a highly selective fashion. Notably, the observed regioselectivity is complementary to conventional radical addition processes. Mechanistic investigations suggest that the photoexcited iridium catalyst facilitated the nickel activation via single-electron transfer.
Cp2ZrCl2- Et3Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
Amirova, Aliya K.,Dzhemilev, Usein M.,Kadikova, Rita N.,Mozgovoj, Oleg S.,Ramazanov, Ilfir R.
, p. 39518 - 39522 (2021/12/27)
The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp2ZrCl2and 1 equivalent of Et3Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp2ZrCl2- Et3Al reagent system to give (1Z,2Z)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis.
Ruthenium-catalyzed synthesis of functional conjugated dienes via addition of two carbene units to alkynes
Paih, Jacques Le,Bray, Chloe Vovard-Le,Derien, Sylvie,Dixneuf, Pierre H.
experimental part, p. 7391 - 7397 (2010/08/05)
The reaction of a variety of alkynes with N2CHSiMe3, in the presence of Cp*RuCl(cod) as the catalyst precursor, leads to the general formation of functional conjugated dienes. This selective formation results from the ruthenium-catal
