110552-78-8Relevant articles and documents
3-heteroalkyl-2,4.quinzaoline-diones
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, (2008/06/13)
A compound is described which is selected from the group consisting of those of the formula: wherein A is a divalent moiety of the formula:, -CnH2n- -CH2CH=CHCH2- or and n is an integer from 2-10, inclusive;, R is hydrogen, oxygen or alkyl having from one to four carbon atoms;, Z is C or N; and when, Z is N, ---is when, Z is C and R is oxygen, ---is ―――; and when, Z is C and R is alkyl, ---is R6 is hydrogen or alkyl having from one to four carbon atoms;, R1 and R2 may be the same or different and may be selected from the group consisting of hydrogen, halogen, trifluoromethyl, alkoxy having from one to four carbon atoms, alkyl having from one to four carbon atoms, nitro and amino; wherein Heteroaryl is wherein R3 and R4 may be selected from hydrogen, alkyl having from one to four carbon atoms, or phenyl; and, X is CH or N, together with the pharmaceutically acceptable salts thereof as well as a process for producing the same and its use for pharmaceutical processes.
Thromboxane synthetase inhibitors and antihypertensive agents. 4. N-[(1H-imidazol-1-yl)alkyl] derivatives of quinazoline-2,4(1H,3H)-diones, quinazolin-4(3H)-ones, and 1,2,3-benzotriazin-4(3H)-ones
Wright Jr.,Tomcufcik,Chan,Marisco,Press
, p. 2277 - 2283 (2007/10/02)
The quinazolinedione, quinazolinone, and 1,2,3-benzotriazinone title compounds were prepared as analogues of N-[(1H-imidazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones which were the subject of a previous report from our laboratories. These compounds were ev