1105686-39-2Relevant academic research and scientific papers
Enantioselective synthesis of 2,6-dideoxy carbasugars based on a desymmetrizing hydroformylation-carbonyl ene cyclization process
Breit, Bernhard,Bigot, Aurelien
supporting information; experimental part, p. 6498 - 6500 (2009/04/13)
A practical one-pot process involving a desymmetrizing hydroformylation with the aid of a chiral catalyst-directing group (CDG*), followed by a carbonyl ene cyclization provides a straightforward access to both enantiomers of the resulting cyclohexanediol; further divergent, highly selective and protecting group-free transformations furnish the carbocyclic analogues of four important 2,6-dideoxysugars. The Royal Society of Chemistry 2008.
