110570-19-9Relevant academic research and scientific papers
Copper-catalyzed cyclization of 3-acylcoumarin hydrazone using air as the oxidant: Efficient synthesis of pyrazole-fused coumarin derivatives
Wang, Hui-Yan,Liu, Xue-Cheng,Huang, Zhi-Bin,Shi, Da-Qing
, p. 380 - 385 (2015/03/30)
An efficient, convenient Cu-catalyzed formation of chromeno[4,3-c]pyrazol-4(1H)-ones is reported. In this atom economic process, readily available 3-acylcoumarin hydrazone is oxidative cyclized by direct C-N bond formation. Air has been successfully used
Synthesis, anticancer activity and photophysical properties of novel substituted 2-oxo-2H-chromenylpyrazolecarboxylates
Kumar, J. Ashok,Saidachary,Mallesham,Sridhar,Jain, Nishant,Kalivendi, Shashi Vardhan,Rao, V. Jayathirtha,Raju, B. China
supporting information, p. 389 - 402 (2013/10/01)
2-Oxo-2H-chromenylpyrazolecarboxylates (8a-h and 12a-zb) have been synthesized by [3 + 2] cycloaddition of 2H-chromenophenylhydrazones (7a-h and 11a-w) with diethyl/dimethylbut-2-ynedioates. Phenylchromeno[4,3-c]pyrazol-4(1H) -ones (13i-n) were prepared from corresponding phenylhydrazones (7a-h) with catalytic amount of piperidine in presence of pyridine as a solvent at 100°C. All the synthesized compounds (8a-h, 12a-zb and 13a-n) were screened for anticancer activity against three human cancer cell lines such as prostate (DU-145), lung adenocarcinoma (A549), and cervical (HeLa) by standard MTT assay method. Further, photophysical properties (UV and fluorescence) for these compounds were discussed.
THE CORRECT SYNTHESIS OF 2,3-DIHYDRO-2-ARYL-4-R-BENZOPYRANOPYRAZOLE-3-ONES.
Colotta, Vittoria,Cecchi, Lucia,Melani, Fabrizio,Palazzino, Giovanna,Filacchioni, Guido
, p. 5165 - 5168 (2007/10/02)
The correct synthesis of the title compounds 1a-b and 2a-b is described.The claimed synthesis of 2a from 2-methyl-3-chromonecarbonitrile is shown not to lead to 2a, as previously reported but to 1,4-dihydro-1-phenyl-3-methylbenzopyranopyrazole-4
