110590-29-9

Basic information

• Product Name: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene-3-carboxylic acid, 1,1-diMethylethyl ester
• Synonyms: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene-3-carboxylic acid, 1,1-diMethylethyl ester;TERT-BUTYL2-OXA-3-AZABICYCLO[2.2.2]OCT-5-ENE-3-CARBOXYLATE(WX120746)
• CAS NO: 110590-29-9
• Molecular Formula: C₁₁H₁₇NO₃
• Molecular Weight: 211.25758
• Mol File: 110590-29-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 280.1±20.0 °C(Predicted)
• Appearance: /
• Density: 1.138±0.06 g/cm3(Predicted)
• PKA: -2.39±0.20(Predicted)
• CAS DataBase Reference: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene-3-carboxylic acid, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene-3-carboxylic acid, 1,1-diMethylethyl ester(110590-29-9)
• EPA Substance Registry System: 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene-3-carboxylic acid, 1,1-diMethylethyl ester(110590-29-9)

Safety Data

• Hazardous Substances Data: 110590-29-9(Hazardous Substances Data)

Upstream product

• 36016-38-3 tert-Butyl N-hydroxycarbamate 
• 1165952-91-9 cyclohexa-1,3-diene 
• 2446-51-7 N-methoxybenzamide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 56239-25-9 (+/-)-2-Oxa-3-azabicyclo[2.2.2]oct-5-ene hydrochloride 
• 7160-44-3 2-oxa-3-azabicyclo[2.2.2]oct-5-ene 

Downstream Products

• 7160-44-3 2-oxa-3-azabicyclo[2.2.2]oct-5-ene 
• 1352201-73-0 (2S)-2-amino-1-(2-oxa-3-azabicyclo[2.2.2]oct-5-en-3-yl)-3-phenylpropan-1-one trifluoroacetate 
• 551000-83-0 tert-butyl (+/-)-(1S,4R)-(4-hydroxycyclohex-2-enyl)carbamate 
• 205878-12-2 [4-Hydroxy-3-(6-methoxy-pyridin-3-yl)-cyclohex-2-enyl]-carbamic acid tert-butyl ester 
• 205878-09-7 [3-(6-Methoxy-pyridin-3-yl)-4-oxo-cyclohex-2-enyl]-carbamic acid tert-butyl ester 
• 205878-01-9 [3-(6-Chloro-pyridin-3-yl)-4-oxo-cyclohex-2-enyl]-carbamic acid tert-butyl ester 
• 205877-96-9 (3-Iodo-4-oxo-cyclohex-2-enyl)-carbamic acid tert-butyl ester 
• 205877-92-5 (4-Oxo-cyclohex-2-enyl)-carbamic acid tert-butyl ester 
• 205878-19-9 (4-Hydroxy-cyclohex-2-enyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Direct evidence for a ruthenium(IV) oxo complex-mediated oxidation of a hydroxamic acid in the presence of phosphine oxide donors

Ruthenium(II) complexes can be used to oxidise N-Boc hydroxylamine in the presence of tert-butylhydroperoxide to the corresponding nitroso dienophile, which is trapped using cyclohexa-1,3-diene as the hetero-Diels-Alder adduct; direct evidence has been obtained for the intervention of a triphenylphosphine oxide-stabilised ruthenium(IV) oxo-complex as the catalytically active species.

The oxidative acylnitroso hetero-diels-alder reaction catalyzed by dirhodium caprolactamate

An effective protocol is described for the generation and in situ Diels-Alder trapping of acylnitroso derivatives. In this procedure, the oxidation of hydroxamic acid is efficiently catalyzed by dirhodium(II) caprolactamate with tert-butyl hydroperoxide (

Copper-catalyzed aerobic oxidation of N-substituted hydroxylamines: Efficient and practical access to nitroso compounds

A general and efficient aerobic oxidation of N-substituted hydroxylamines is described. The mild reaction conditions employed provide a catalytic and sustainable alternative to stoichiometric oxidation methods to gain access to a range of nitroso compound

Efficient cleavage of the N-O bond of 3,6-dihydro-1,2-oxazines mediated by some α-hetero substituted carbonyl compounds in mild conditions

The efficient cleavage of the N-O bond of some nitroso Diels-Alder cycloadducts has been achieved in mild conditions, mediated either by 2,2-dimethyl-1,3-dioxan-5-one or 1,3-dithiolane-2-carboxaldehyde. These new and purely organic conditions allow an exc