110615-11-7Relevant academic research and scientific papers
The direct synthesis of unsymmetrical vicinal diamines from terminal alkynes: A tandem sequential approach for the synthesis of imidazolidinones
Lee, Alison V.,Sajitz, Melanie,Schafer, Laurel L.
experimental part, p. 97 - 104 (2009/07/18)
The combination of titanium-catalyzed anti-Markovni- kov hydroamination of terminal alkynes with the Strecker reaction is used in the synthesis of unsymmetrical vicinal diamines via the one-pot synthesis of α-cyanoamines. This methodology is further applied to the efficient synthesis of imidazolidinones. An easy-to-use bis(amidate)titanium precatalyst permits efficient approaches to heterocyclic chemistry from terminal alkynes. Georg Thieme Verlag Stuttgart.
Highly enantioselective and diastereoselective synthesis of β-amino acid esters and β-lactams from achiral esters and imines
Corey,Decicco, Carl P.,Newbold, Ronald C.
, p. 5287 - 5290 (2007/10/02)
The reaction of S-tert-butyl thiopropionate with a number of N-benzyl or N-allyl aldimines (4) as promoted by the chiral diazaborolidine 1 and triethylamine afforded the β-amino acid esters 5 with high diastereoselectivity and enantioselectivity, providin
