110623-43-3Relevant academic research and scientific papers
An improved method for the synthesis of 5-aryl-3-methyl-2-methylimino-1,3,4-oxadiazoles
Kane,Staeger
, p. 1 - 11 (1992)
5-Aryl-3-methyl-2-methylimino-1,3,4-oxadiazoles were prepared in 54-81% yields by the mercuric oxide-induced cyclizations of 1-aroyl-2,4,-dimethylthiosemicarbazides.
5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
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, (2008/06/13)
This invention relates to the enhancement of memory and cognition and the treatment of Alzheimer''s disease and Wernicke-Korsakoff syndrome by administration of 5-(R n -phenyl)-4-alkyl-3H-1,2,4-triazole-3-thiones of the formula STR1 wherein R is halogen, trifluoromethyl, C 1-4 lower alkyl orC 1-4 lower alkoxy,n is zero, 1 or 2, andR 2 represents hydrogen or C 1-3 lower alkyl; andR 4 independently represents C 1-3 lower alkyl.
5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones useful as antidepressants
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, (2008/06/13)
This invention relates to novel 5-(Rn -phenyl)-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and to their use as antidepressants.
Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
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, (2008/06/13)
This invention relates to a novel method for the treatment of hemorrhagic and thrombotic thrombocytosis by means of administration of a 5-(4-chlorophenyl)-2,4-dimethyl-3H-1,2,4-triazole-3-thione.
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as Potential Antidepressant Agents
Kane, John M.,Dudley, Mark W.,Sorensen, Stephen M.,Miller, Francis P.
, p. 1253 - 1258 (2007/10/02)
A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones was prepared and evaluated for potential antidepressant activity.Members of this series were generally prepared by the alkaline ring closures of the corresponding 1-aroylthiosemicarbazides.Several
5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
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, (2008/06/13)
This invention relates to novel 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones, to the intermediates and processes for their preparation, and to their use as antidepressants.
