110645-14-2

Basic information

• Product Name: Phenol, 2-mercapto-4-(phenylmethoxy)-
• CAS NO: 110645-14-2
• Molecular Formula: C13H12O2S
• Molecular Weight: 232.303
• Mol File: 110645-14-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 2-mercapto-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-mercapto-4-(phenylmethoxy)-(110645-14-2)
• EPA Substance Registry System: Phenol, 2-mercapto-4-(phenylmethoxy)-(110645-14-2)

Safety Data

• Hazardous Substances Data: 110645-14-2(Hazardous Substances Data)

Upstream product

• 321974-15-6 5-benzyloxybenzo[d][1,3]oxathiol-2-one 
• 106-51-4 p-benzoquinone 
• 7735-56-0 5-hydroxybenzo[d][1,3]oxathiol-2-one 

Downstream Products

• 719311-32-7 2-(5-benzyloxy-2-hydroxy-phenylsulfanyl)-3-methyl-1-(4-triisopropylsilanyloxy-phenyl)-butan-1-one 
• 474527-57-6 2-(5-benzyloxy-2-hydroxy-phenylsulfanyl)-2-pyridin-3-yl-1-(4-triisopropylsilanyloxy-phenyl)-ethanone 
• 412051-74-2 2-(5-benzyloxy-2-hydroxy-phenylsulfanyl)-2-pyridin-4-yl-1-(4-triisopropylsilanyloxy-phenyl)-ethanone 
• 744256-36-8 6-(5-benzyloxy-2-hydroxy-phenylsulfanyl)-5-oxo-6-(4-triisopropylsilanyloxy-phenyl)-hexanenitrile 
• 412051-73-1 2-(5-benzyloxy-2-hydroxy-phenylsulfanyl)-2-cyclopentyl-1-(4-triisopropylsilanyloxy-phenyl)-ethanone 
• 412051-72-0 2-(5-benzyloxy-2-hydroxy-phenylsulfanyl)-2-cyclohexyl-1-(4-triisopropylsilanyloxy-phenyl)-ethanone 
• 744256-21-1 4-benzyloxy-2-(4-benzyloxy-benzylsulfanyl)-phenol 
• 1616377-40-2 2-phenylbenzo[1,4]oxathiin-6-ol 
• 1616377-44-6 C₂₁H₁₈O₃S 
• 474527-74-7 1-(2-{4-[(2S,3R)-6-Benzyloxy-3-(3-triisopropylsilanyloxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-2-yl]-phenoxy}-ethyl)-pyrrolidine 
• 474527-67-8 (+)-4-((2S,3R)-6-(benzyloxy)-3-{3-[(triisopropylsilyl)oxy] phenyl}-2,3-dihydro-1,4-benzoxathiin-2-yl) phenol 

Relevant articles and documents

Thiaflavan scavenges radicals and inhibits DNA oxidation: A story from the ferrocene modification

4-Thiaflavan is a sulfur-substituted flavonoid with a benzoxathiin scaffold. The aim of this work is to compare abilities of sulfur and oxygen atom, hydroxyl groups, and ferrocene moiety at different positions of 4-thiaflavan to trap radicals and to inhibit DNA oxidation. It is found that abilities of thiaflavans to trap radicals and to inhibit DNA oxidation are increased in the presence of ferrocene moiety and are further improved by the electron-donating group attaching to thiaflavan skeleton. It can be concluded that the ferrocene moiety plays the major role for thiaflavans to be antioxidants even in the absence of phenolic hydroxyl groups. On the other hand, the antioxidant effectiveness of phenolic hydroxyl groups in thiaflavans can be improved by the electron-donating group. The influences of sulfur and oxygen atoms in thiaflavans on the antioxidant property of para-hydroxyl group exhibit different manners when the thiaflavans are used to trap radicals and to inhibit DNA oxidation.

Estrogen receptor modulators

The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.