1107063-66-0Relevant academic research and scientific papers
Highly efficient synthesis of 3,4-dihydro-2(1H)-quinolinone derivatives under microwave heating
Zhu, Xiao-Tong,Li, Qiu-Yun,Jiang, Bo,Tu, Shu-Jiang
experimental part, p. 1615 - 1628 (2012/08/29)
A sequential three-component reaction of aromatic aldehydes with aromatic amine, and Meldrum's acid in EtOH under microwave irradiation has been developed. In this one-pot reaction, a series of 3,4-dihydro-2(1H)-quinolinone derivatives were synthesized with high chemical yields. The present green synthesis shows several advantages including operational simplicity and fast reaction rate, which makes it a useful and attractive process for library generation for drug discovery.
Sodium acetate catalyzed multicomponent cyclization of aromatic aldehydes, acetone and meldrum acid
An, Lin,Yang, Feng,Yao, Rong,Yan, Chaoguo
experimental part, p. 2451 - 2454 (2011/10/03)
The sodium acetate catalyzed three-component reaction of aromatic aldehyde, acetone and Meldrum acid or spirolactone at room temperature gave stereospecific 7,11-cis-diaryl-2,4-dioxaspiro[5,5]undecane-1,5,9-triones in a very efficient manner. The sodium a
A new domino autocatalytic reaction leading to polyfunctionalized spiro[5.5]undecanes and dispiro[4.2.5.2]pentadecanes
Jiang, Bo,Hao, Wen-Juan,Zhang, Jin-Peng,Tu, Shu-Jiang,Shi, Feng
supporting information; experimental part, p. 2195 - 2201 (2009/09/04)
A new domino autocatalytic reaction of imines with Meldrum's acid was described. In this reaction, a series of polycyclic spiro[5.5]undecane-1,5,9- trione and dispiro[4.2.5.2]pentadecane-9,13-dione derivatives, with remarkable diastereoselectivity, were s
