110762-24-8Relevant articles and documents
Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery
Nordqvist, Anneli,Nilsson, Mikael T.,Roettger, Svenja,Odell, Luke R.,Krajewski, Wojciech W.,Evalena Andersson,Larhed, Mats,Mowbray, Sherry L.,Karlen, Anders
, p. 5501 - 5513 (2008/12/20)
A combination of a literature survey, structure-based virtual screening and synthesis of a small library was performed to identify hits to the potential antimycobacterial drug target, glutamine synthetase. The best inhibitor identified from the literature
PHOSPHORUS-CONTAINING AMINOCARBOXYLIC ACIDS. COMMUNICATION IV. A CONVENIENT METHOD OF PHOSPHONIC ACIDS SYNTHESIS
Ragulin, V. V.,Bofanova, M. E.,Tsvetkov, Eugene N.
, p. 237 - 242 (2007/10/02)
The communication is concerned with the synthesis of phosphonic aminocarboxylic acids by phosphorylation of diethyl ω-halogen alkyl acetamidomalonates with tris(trimethylsilyl) phosphite, followed by alcoholysis and acid hydrolysis of the resulting intermediate esters.Key words: Phosphonic aminocarboxylic acids; tris(trimethylsilyl) phosphite; ω-halogenalkyl acetamidomalonates; phosphorylation; alcoholysis, hydrolysis
