1107627-02-0

Basic information

• Product Name: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole
• Synonyms: 1-Methyl-1H-benzimidazole-5-boronic acid pinacol ester;1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole;1-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]iMidazole;1-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-benzo[d]iMidazole
• CAS NO: 1107627-02-0
• Molecular Formula: C₁₄H₁₉BN₂O₂
• Molecular Weight: 258.12386
• Product Categories: 6
• Mol File: 1107627-02-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 400.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.11
• Storage Temp.: 2-8°C
• PKA: 5.26±0.10(Predicted)
• CAS DataBase Reference: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole(1107627-02-0)
• EPA Substance Registry System: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole(1107627-02-0)

Safety Data

• Hazardous Substances Data: 1107627-02-0(Hazardous Substances Data)

Usage

General Description

1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole is a chemical compound with the molecular formula C15H20BNO2. It is a benzimidazole derivative that contains a boron atom. 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole is often used as a ligand in various chemical reactions and catalytic processes due to its ability to coordinate with transition metal ions. It has also been studied for its potential applications in organic synthesis and pharmaceutical chemistry. This chemical has a wide range of potential uses in industry and research, and its versatile properties make it a valuable tool in various chemical applications.

Upstream product

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• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 53484-15-4 5-bromo-1-methyl-1H-benzo[d]imidazole 
• 73183-34-3 bis(pinacol)diborane 

Relevant articles and documents

FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF

The present disclosure generally relates to improved synthesis of fused bicyclic Raf inhibitors of formula (I), (I-A), (I-B), (II), or (III), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof. The disclosure also relates to method o

PYRAZOLO[1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted pyrazolo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrazolo[1,5-a]pyrimidinyl carboxamide compounds described herein include 2-heterocyclyl-4-alkyl-pyrazolo[1,5-a]pyrirnidine-3-carboxarnide compounds and variants thereof.

CINNOLINE DERIVATIVES AS AS BTK INHIBITORS

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined in the specification. The compounds are inhibitors of Bruton's tyrosine