1107640-95-8Relevant academic research and scientific papers
Palladium-Catalyzed Direct β-C?H Arylation of Ketones with Arylboronic Acids in Water
Hu, Xiaoyun,Yang, Xiaobo,Dai, Xi-Jie,Li, Chao-Jun
supporting information, p. 2402 - 2406 (2017/07/22)
A palladium-catalyzed direct β-C?H arylation of ketones was developed under mild conditions in water, featuring commercially available arylboronic acids as nucleophilic aryl sources and o-iodoxybenzoic acid as the oxidant. The method provides a concise route to access β-arylated ketones. Preliminary studies indicated that direct asymmetric β-C?H arylation of ketones could be achieved by this strategy. (Figure presented.).
PH-Dependent conjugate addition of arylboronic acids to α,β-unsaturated enones catalyzed by a reusable palladium(II)/cationic 2,2'-bipyridyl system in water under air
Huang, Shao-Hsien,Wu, Tzu-Min,Tsai, Fu-Yu
experimental part, p. 619 - 624 (2010/11/04)
A reusable Pd(NH3)2Cl2/cationic 2,2'-bipyridyl system for the catalysis of the conjugate addition of arylboronic acids to α,β-unsaturated enones in water under air was developed. Addition of arylboronic acids to both cyclic and acyclic enones progressed smoothly, providing the products in good to high yields, the best result being obtained when HBF4 was used to adjust the pH value to 1.0. After the reaction, the residual aqueous solution could be reused several times,making the reaction greener and reducing wastage of precious metals. Copyright
Selective Heck reaction of aryl bromides with cyclopent-2-en-1-one or cyclohex-2-en-1-one
Fall, Yacoub,Doucet, Henri,Santelli, Maurice
experimental part, p. 489 - 495 (2009/04/07)
The selective Heck reaction of cyclopent-2-en-1-one or cyclohex-2-en-1-one with aryl bromides gives a simple access to the corresponding 3-arylcycloalk-2-en-1-ones. The choice of the base was found to be crucial to avoid the formation of 3-arylcyclopentan
