1107650-55-4Relevant academic research and scientific papers
Synthesis of the perdeuterated cellulose solvents N-methylmorpholine N-oxide (NMMO-d11) and N,N-dimethylacetamide (DMAC-d9)
Adelwoehrer, Christian,Yoneda, Yuko,Nakatsubo, Fumiaki,Rosenau, Thomas
, p. 28 - 32 (2008)
The synthesis of the perdeuterated cellulose solvents NMMO-d11 (9) and N,N-dimethylacetamide-d9 (14) is described. NMMO-d 11 was obtained according to a five-step approach from non-labeled diglycolic acid (1) via diethylene glycole-d8 (4) and its bis-tosylate (5), which underwent cyclization with benzylamine to N-benzylmorpholine (6). The removal of the benzyl protecting group, methylation and N-oxidation completed the synthesis. DMAc-d9 (14) was obtained from deuterated acetic acid (10) and dimethylamine-carbon dioxide complex (17) with acidic alumina as the catalyst according to a solvent-free gas-solid reaction. Copyright
