110793-80-1

Basic information

• Product Name: (5R)-5-but-3-en-1-yldihydrofuran-2(3H)-one
• Synonyms: (5R)-5-(But-3-en-1-yl)dihydrofuran-2(3H)-one; 2(3H)-furanone, 5-(3-buten-1-yl)dihydro-, (5R)-; (R)-5-(but-3-en-1-yl)dihydrofuran-2(3H)-one
• CAS NO: 110793-80-1
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.1797
• Mol File: 110793-80-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 242.457°C at 760 mmHg
• Flash Point: 93.578°C
• Density: 0.988g/cm³
• Vapor Pressure: 0.034mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: (5R)-5-but-3-en-1-yldihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-5-but-3-en-1-yldihydrofuran-2(3H)-one(110793-80-1)
• EPA Substance Registry System: (5R)-5-but-3-en-1-yldihydrofuran-2(3H)-one(110793-80-1)

Safety Data

• Hazardous Substances Data: 110793-80-1(Hazardous Substances Data)

Usage

General Description

(5R)-5-but-3-en-1-yldihydrofuran-2(3H)-one is a chemical compound with the molecular formula C7H10O2. It is a butenolide, which is a class of organic compounds containing a five-membered lactone ring with a double bond. (5R)-5-but-3-en-1-yldihydrofuran-2(3H)-one has a chiral center and exists as a pair of enantiomers. It is commonly used as a flavoring agent in the food industry, providing a fruity and caramel-like aroma. Additionally, it is also utilized in the production of fragrances and as a precursor in organic synthesis. Studies have shown potential anti-inflammatory and anticancer properties of this compound, making it a subject of interest for future pharmaceutical applications.

Upstream product

• 10353-53-4 1,2-epoxy-5-hexene 
• 1424343-96-3 C₁₁H₁₆O₄ 
• 105-53-3 diethyl malonate 
• 137688-20-1 (R)-2-(but-3-en-1-yl)oxirane 
• 58879-36-0 (S)-(+)-γ-iodometil-γ-butirrolattone 
• 24850-33-7 allyltributylstanane 

Downstream Products

• 914922-88-6 C₁₇H₃₅NO₃Si 
• 220106-21-8 2-(2-bromo-allyl)-4-(tert-butyl-diphenyl-silanyloxy)-1-pyrrolidin-1-yl-oct-7-en-1-one 
• 220106-42-3 2-benzyl-4-(tert-butyl-diphenyl-silanyloxy)-1-pyrrolidin-1-yl-oct-7-en-1-one 
• 220106-36-5 4-(tert-butyl-diphenyl-silanyloxy)-2-methyl-1-pyrrolidin-1-yl-oct-7-en-1-one 
• 201344-60-7 4-(tert-butyl-diphenyl-silanyloxy)-1-pyrrolidin-1-yl-oct-7-en-1-one 
• 69830-91-7 (R)-4-dodecanolide 

Relevant articles and documents

Process development of halaven: Synthesis of the C14-C35 fragment via iterative nozaki-hiyama-kishi reaction-williamson ether cyclization

Multikilogram manufacturing process of the Halaven C14-C35 fragment is described. The synthesis features convergent assembly of subunits by iterative asymmetric Ni/Cr-mediated coupling executed in fixed equipment. Georg Thieme Verlag Stuttgart - New York.

A direct method for the conversion of terminal epoxides into γ-butanolides

A new and efficient process for the conversion of terminal epoxides to γ-butanolides is described involving Lewis acid promoted epoxide ring-opening by 1-morpholino-2-trimethylsilyl acetylene. Addition of a terminal epoxide to a solution of the ynamine an

Conversion of hydroxy nitriles to lactones using Rhodococcus rhodochrous whole cells

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