1108147-63-2Relevant articles and documents
Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl] -1H-benzimidazole: Design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent
Hayashi, Shigeo,Hirao, Akiko,Imai, Aki,Nakamura, Hiroshi,Murata, Yoshinori,Ohashi, Katsuyo,Nakata, Eriko
experimental part, p. 610 - 625 (2009/12/29)
An endogenous heptadecapeptide, nociceptin/orphanin FQ (N/OFQ), and a G-protein-coupled receptor, N/OFQ peptide (NOP) receptor [or opioid-receptor-like-1 (ORL1) receptor], have been described in terms of its structure, distribution, and pharmacology. Thus