110830-23-4Relevant academic research and scientific papers
4-Quinolones as noncovalent inhibitors of high molecular mass penicillin-binding proteins
Shilabin, Abbas G.,Dzhekieva, Liudmila,Misra, Pushpa,Jayaram,Pratt
, p. 592 - 595 (2012)
Penicillin-binding proteins (PBPs) are important bacterial enzymes that carry out the final steps of bacterial cell wall assembly. Their DD-transpeptidase activity accomplishes the essential peptide cross-linking step of the cell wall. To date, all attemp
A CONVENIENT SYNTHESIS OF PYRROLOQUINOLINE-1,5-DIONES AND ACRIDINE-1,9-DIONES
Deady, Leslie W.,Werden, Dianne M.
, p. 319 - 328 (2007/10/02)
The reaction of anilines with EtO2C-CH2-CO-(CH2)n-CO2Et gives the corresponding quinolinones.Further cyclization gives the title compounds (n=2 and 3, respectively).The reaction has been extended to 6-methyl-2-pyridinamine and 1-(p-methylphenoxy)isoquinol
