1108615-82-2

Upstream product

• 1108615-80-0 (R)-tert-butyl ((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)carbamate 
• 1108615-88-8 (R)-2-methyl-N-((R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)propane-2-sulfinamide 
• 21239-95-2 3-oxo-2-aza-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester 
• 21129-88-4 2-methyl-3-oxo-2-aza-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester 
• 1108615-84-4 2-methyl-3-oxo-2-azabicyclo[2.2.2]octane-1-carbaldehyde 
• 1108615-86-6 (R)-2-methyl-N-((R)-(2-methyl-3-oxo-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)propane-2-sulfinamide 

Downstream Products

• 1108615-54-8 (R)-2,6-dimethyl-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)benzamide 
• 1108615-59-3 2-Chloro-N-[(R)-(2-methyl-2-aza-bicyclo[2.2.2]oct-1-yl)-phenyl-methyl]-3-trifluoromethylbenzamide 
• 1108615-51-5 (R)-2,3-dichloro-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)benzamide 
• 1239321-49-3 (R)-2,3-dichloro-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)isonicotinamide 
• 1239321-22-2 (R)-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)-2-(methylthio)nicotinamide 
• 1239321-71-1 C₂₃H₂₉N₃O 
• 1239321-69-7 C₂₂H₂₆ClN₃O₂ 
• 1239321-24-4 (R)-3-bromo-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)isonicotinamide 
• 1108615-52-6 (R)-2,6-dichloro-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)benzamide 
• 1239321-48-2 (R)-3,5-dichloro-N-((2-methyl-2-azabicyclo[2.2.2]octan-1-yl)(phenyl)methyl)isonicotinamide 
• 1108615-32-2 2-Amino-6-chloro-N-[(R)-(2-methyl-2-aza-bicyclo[2.2.2]oct-1-yl)-phenyl-methyl]-benzamide 

Relevant academic research and scientific papers

Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1

A series of isoquinuclidine benzamides as glycine uptake inhibitors for the treatment of schizophrenia are described. Potency, lipophilicity, and intrinsic human microsomal clearance were parameters for optimization. Potency correlated with the nature of

2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF

This invention relates to 2-aza-bicyclo [2.2.2] octane compounds (and salts thereof), the process for making such a compound and pharmaceutical compositions comprising such a compound. The invention also relates to the use of the compounds for modulating

Novel Compounds 894

The invention relates to 2-aza-bicyclo[2.2.2]octane compounds and uses thereof. Particularly the invention relates to such compounds and their uses as pharmaceuticals in treating pyshoses such as schizophrenia and other diseases, disorders, or conditions.