110878-71-2

Usage

Uses

Used in Pharmaceutical Industry:
4-(3-Hydroxyphenyl)piperidine is used as a building block for the synthesis of various pharmaceuticals and biologically active compounds due to its unique chemical structure and pharmacological properties.
Used in Medicinal Chemistry Research:
4-(3-Hydroxyphenyl)piperidine is used as a research tool in medicinal chemistry for the development of new drugs, particularly for the treatment of neurological and psychiatric disorders, owing to its potential applications in drug discovery and development efforts.
Used in Drug Development:
4-(3-Hydroxyphenyl)piperidine is used in the development of new drugs for the treatment of neurological and psychiatric disorders, leveraging its unique chemical structure and pharmacological properties to enhance drug efficacy and target specific therapeutic areas.

Upstream product

• 325808-20-6 4-(3-methoxyphenyl)piperidine hydrogen chloride salt 
• 1276045-26-1 4-(3-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1307314-95-9 4-(3-methoxy-phenyl)-piperidine trifluoroacetate 
• 766-85-8 3-methoxy-1-iodobenzene 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 194669-45-9 4-(3-methoxy-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1026155-24-7 4-(3-hydroxyphenyl)-1-(3-pyridinecarbonyl)piperidine 
• 325808-28-4 4-(3-hydroxyphenyl)-1-(2,4,6-trifluorobenzoyl)piperidine 
• 325808-30-8 1-[3,5-di(tert-butyl)-4-hydroxybenzoyl]-4-(3-hydroxyphenyl)piperidine 
• 325808-21-7 1-(4-fluorobenzoyl)-4-(3-hydroxyphenyl)piperidine 
• 325808-26-2 4-(3-hydroxyphenyl)-1-[4-(trifluoromethyl)benzoyl]piperidine 
• 325808-34-2 4-(3-hydroxyphenyl)-1-(4-methylbenzoyl)piperidine 
• 325808-22-8 1-(4-chlorobenzoyl)-4-(3-hydroxyphenyl)piperidine 
• 325808-27-3 1-(2,4-difluorobenzoyl)-4-(3-hydroxyphenyl)piperidine 
• 325808-29-5 1-(3-fluorobenzoyl)-4-(3-hydroxyphenyl)piperidine 
• 325808-25-1 1-(4-bromobenzoyl)-4-(3-hydroxyphenyl)piperidine 
• 325808-23-9 1-(2-fluorobenzoyl)-4-(3-hydroxyphenyl)piperidine 
• 250732-81-1 N-hexyl-4-(3-hydroxyphenyl)piperidine 
• 161609-59-2 (S)-N-[2-(3,4-Dichlorophenyl)-4-[4-(3-hydroxyphenyl)piperidino]butyl]-N-methylbenzamide hydrochloride 
• 1276045-12-5 cyclopropyl-[4-(3-hydroxy-phenyl)-piperidin-1-yl]-methanone 

Relevant academic research and scientific papers

Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl- cyclopropane carboxamide derivatives as novel melatonin receptor ligands

Two series of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives exhibiting diverse functionality at rat MT1 and MT2 receptors are reported. Compounds 11f and 18b (MT 1/MT2 agonist) have human microsomal intrinsic clearance comparable to ramelteon.

Novel 4-phenylpiperidines for the treatment of pruritic dermatoses

Novel compounds having general formula (I), and pharmaceutically and veterinarily acceptable salts thereof wherein R 1, R 2, R 3, W, Y 1, Y 2, X, n and y are as defined above and processes for their preparation and intermediate compounds prepared therein. The novel compounds are useful for having utility in the treatment. of pruritic dermatoses including allergic dermatitis and atopy in animals and humans

New strong fibrates with piperidine moiety

New fibrates containing piperidine, 4-hydroxypiperidine, piperidin-3-ene, and piperazine moieties in the structures were synthesized and evaluated. Among the synthesized compounds, 2-[3-[1-(4-fluorobenzoyl)-piperidin-4yl]phenoxy]-2-methylpropanoic acid (9