110894-23-0

Basic information

• Product Name: 3-(4,4'-DIMETHOXYTRITYL)PROPANDIOL-1-N,N-DIISOPROPYL (BETA-CYANOETHYL) PHOSPHORAMIDITE
• Synonyms: 3-(4,4'-DIMETHOXYTRITYL)PROPANDIOL-1-N,N-DIISOPROPYL (BETA-CYANOETHYL) PHOSPHORAMIDITE;SPACER-C 3 CEP;PROPYL LINKER, C3 SPACER
• CAS NO: 110894-23-0
• Molecular Formula: C33H43N2O5P
• Molecular Weight: 578.68
• Mol File: 110894-23-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 620.7±55.0 °C(Predicted)
• Appearance: /
• PKA: 3.75±0.70(Predicted)
• CAS DataBase Reference: 3-(4,4'-DIMETHOXYTRITYL)PROPANDIOL-1-N,N-DIISOPROPYL (BETA-CYANOETHYL) PHOSPHORAMIDITE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4,4'-DIMETHOXYTRITYL)PROPANDIOL-1-N,N-DIISOPROPYL (BETA-CYANOETHYL) PHOSPHORAMIDITE(110894-23-0)
• EPA Substance Registry System: 3-(4,4'-DIMETHOXYTRITYL)PROPANDIOL-1-N,N-DIISOPROPYL (BETA-CYANOETHYL) PHOSPHORAMIDITE(110894-23-0)

Safety Data

• Hazardous Substances Data: 110894-23-0(Hazardous Substances Data)

Usage

Properties

1. Chemical compound used in the synthesis of oligonucleotides
2. Phosphoramidite derivative of a protected nucleoside
3. Utilized in solid-phase synthesis of DNA and RNA
4. Critical for efficient and high-quality production of synthetic oligonucleotides
5. Known for stability and reliability in oligonucleotide synthesis
6. Commonly used in DNA and RNA synthesis for biological and pharmaceutical applications

Specific content

1. 3-(4,4'-dimethoxytrityl)propandiol-1-N,N-diisopropyl (beta-cyanoethyl) phosphoramidite
2. Phosphoramidite building block
3. Used in molecular biology research
4. Important tool in oligonucleotide synthesis
5. Enables the synthesis of DNA and RNA
6. Ensures the stability and quality of synthesized oligonucleotides.

Upstream product

• 102691-36-1 N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite 
• 110675-04-2 3<(4,4'-dimethoxytrityl)oxy>propan-1-ol 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 

Downstream Products

• 1233482-83-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-[3-[(2-cyanoethyl)-N,N-diisopropylphosphoramidothioyl]prop-1-oxy]-(N,N-diisopropylamino)phosphinyl-2'-deoxythymidine 

Relevant articles and documents

RNA interference agent, method for producing same, and use therefor

Provided is an RNA interference agent, with which a suppression effect on the off-target effect can be obtained with a simple system. The disclosures relate to an RNA interference agent provided with a single-stranded oligonucleotide passenger strand having one or two or more PAZ domain low-affinity units at the 3′-end.

Enzymatic combinatorial nucleoside deletion scanning mutagenesis of functional RNA

We describe a general and simple method to identify catalytically and structurally important nucleotides in functional RNAs. Our approach is based on statistical replacement of each nucleoside with a non-nucleosidic spacer (C3 linker, Δ), followed by sepa

Synthesis, gene-silencing activity and nuclease resistance of 3′-3′-linked double short hairpin RNA

To improve the nuclease resistance of siRNA while reducing its induction of an innate immune response and maintaining its biological activity for possible therapeutic application, we designed and synthesized a series of double short hairpin RNAs (dshRNAs)