1109000-10-3Relevant articles and documents
Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas
Ekoue-Kovi, Kekeli,Yearick, Kimberly,Iwaniuk, Daniel P.,Natarajan, Jayakumar K.,Alumasa, John,de Dios, Angel C.,Roepe, Paul D.,Wolf, Christian
experimental part, p. 270 - 283 (2011/02/28)
We report the synthesis and in vitro antimalarial activities of more than 50 7-chloro-4-aminoquinolyl-derived sulfonamides 3-8 and 11-26, ureas 19-22, thioureas 23-26, and amides 27-54. Many of the CQ analogues prepared for this study showed submicromolar