110904-84-2

Upstream product

• 578-57-4 2-bromoanisole 
• 3348-44-5 bis(N,N-dimethylamino)chlorophosphine 

Downstream Products

• 192824-20-7 (3aR,7aR)-1,3-dimethyl-2-o-methoxyphenyl-2,3,3a,4,5,6,7,7a-octahydro-1H-1,3,2-benzodiazaphosphole 
• 207129-48-4 (2S,5S)-2-(2-hydroxyphenyl)-3-phenyl-1,3-diaza-2-phosphabicyclo[3.3.0]octane 2-oxide 
• 295795-88-9 (2S,5S)-2-(2-anisyl)-3-phenyl-1,3-diaza-2-phosphabicyclo[3.3.0]octane 2-oxide 

Relevant academic research and scientific papers

Asymmetric hydrogenation of ketones using a ruthenium(II) catalyst containing BINOL-derived monodonor phosphorus-donor ligands

(Chemical Equation Presented) A series of ruthenium(II) complexes containing BINOL-based monodonor phosphorus ligands have been prepared and applied to the asymmetric catalysis of the hydrogenation of aryl/alkyl ketones. The best ligands for this application are those which contain an aromatic groups with either a methoxide or bromide on the ortho position. Using these ligands, alcohols with ee's of up to 99% are formed.

Synthesis and applications to asymmetric catalysis of a series of mono- and bis(diazaphospholidine) ligands

The synthesis of a series of closely related mono- and bis(diazaphospholidine) ligands has been achieved using the condensation of a diamine with a bis(dimethylamino)arylphosphine. The resulting ligands have given excellent results in palladium-catalysed allylic substitution reactions to form C-C bonds (up to 89% ee) and C-N bonds (up to 78% ee).