110943-79-8

Basic information

• Product Name: Ethyl-3-(2-hydroxy-5-nitroanilino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate
• Synonyms: Ethyl-3-(2-hydroxy-5-nitroanilino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate
• CAS NO: 110943-79-8
• Molecular Weight: 428.297
• Mol File: 110943-79-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethyl-3-(2-hydroxy-5-nitroanilino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl-3-(2-hydroxy-5-nitroanilino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate(110943-79-8)
• EPA Substance Registry System: Ethyl-3-(2-hydroxy-5-nitroanilino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate(110943-79-8)

Safety Data

• Hazardous Substances Data: 110943-79-8(Hazardous Substances Data)

Upstream product

• 94695-50-8 ethyl 3-(2,3,4,5-tetrafkuorophenyl)-3-oxopropanoate 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 94695-48-4 2,3,4,5-tetrafluorobenzoyl chloride 
• 122-51-0 orthoformic acid triethyl ester 
• 138998-47-7 ethyl α<(N,N-dimethylamino)methylene>-2,3,4,5-tetrafluoro-β-oxobenzenepropanoate 

Relevant articles and documents

HYDRAZIDE COMPOUNDS AND USES THEREOF

This application relates to certain novel polycyclic compounds that interact with quadruplex-forming regions of polynucleotides and thereby inhibit translation of genetic information into polypeptides. These compounds can thus provide anticancer and antibacterial and antiviral effects. The invention includes novel compounds and pharmaceutical compositions, and methods of using them to treat cancer and other conditions.

Quinobenzoxazine, antineoplastic agents

Quinobenzoxazine, derivatives of the formula STR1 as well as the pharmaceutically acceptable salts, esters, amides and prodrugs thereof are disclosed, wherein R1 is hydrogen or a carboxy-protecting group, R2 and R3 are substitutents, A is oxygen, Z is a halogen or a nitrogen-containing group, X is hydrogen, halogen or alkyl, and W is hydrogen, alkyl, amino or halogen. The compounds have potent antineoplastic activity.