110999-53-6 Usage
Type
Organic compound
Functional Groups
Nitro group, hydroxyethylamine
Class
Pyrazoloacridine compounds
Structure
Contains a dihydropyrazole ring
Biological Activities
Potential pharmaceutical or research applications
Properties
Further analysis and testing required for precise applications
Check Digit Verification of cas no
The CAS Registry Mumber 110999-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,9,9 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 110999-53:
(8*1)+(7*1)+(6*0)+(5*9)+(4*9)+(3*9)+(2*5)+(1*3)=136
136 % 10 = 6
So 110999-53-6 is a valid CAS Registry Number.
110999-53-6Relevant articles and documents
2-(Aminoalkyl)-5-nitropyrazoloacridines, a New Class of Anticancer Agents
Capps, David B.,Dunbar, James,Kesten, Suzanne R.,Shillis, Joan,Werbel, Leslie M.,et al.
, p. 4770 - 4778 (2007/10/02)
2-(Aminoalkyl)-5-nitropyrazoloacridines were prepared from substituted anilines via the 1-chloro-4-nitroacridones followed by condensation with hydrazines.Impressive activity was demonstrated for the 9-hydroxy, 9-alkoxy, and 9-acyloxy analogs in vitro on a L1210 leukemia line and in vivo against the P388 leukemia.Advanced studies led to the selection of 3bbb for clinical trial.