1110602-52-2Relevant academic research and scientific papers
Urea based CCR3 antagonists employing a tetrahydro-1,3-oxazin-2-one spacer
Dhar, T.G. Murali,Yang, Guchen,Davies, Paul,Malley, Mary F.,Gougoutas, Jack Z.,Wu, Dauh-Rurng,Barrish, Joel C.,Carter, Percy H.
, p. 96 - 99 (2009)
Conformational restriction of open chain analogs with a more polar tetrahydro-1,3-oxazin-2-one spacer led to the identification of potent urea-based CCR3 antagonists that exhibited excellent selectivity over binding to CYP2D6. The in vitro binding and eos
