1110630-98-2Relevant articles and documents
Preparation of bicyclic 1,2,4-trioxanes from γ,δ-unsaturated ketones
Ramirez, Armando P.,Thomas, Andrew M.,Woerpel
, p. 507 - 510 (2009)
(Chemical Equation Presented) Treatment of γ,δ-unsaturated ketones with hydrogen peroxide and acid provides a rapid entry into the medicinally important 1,2,4-trioxane structure. Alkene substitution that stabilizes carbocationic intermediates proved to be important for the success of this transformation.
