1110700-49-6Relevant articles and documents
Nucleophilic Ring Opening of Donor-Acceptor Cyclopropanes Catalyzed by a Br?nsted Acid in Hexafluoroisopropanol
Richmond, Edward,Vukovi?, Vuk D.,Moran, Joseph
, p. 574 - 577 (2018/02/10)
A general, Br?nsted acid catalyzed method for the room temperature, nucleophilic ring opening of donor-acceptor cyclopropanes in fluorinated alcohol solvent, HFIP, is described. Salient features of this method include an expanded cyclopropane scope, including those bearing single keto-acceptor groups and those bearing electron-deficient aryl groups. Notably, the catalytic system proved amenable to a wide range of nucleophiles including arenes, indoles, azides, diketones, and alcohols.
Rhodium-catalyzed cyclopropanation of alkenes with dimethyl diazomalonate
Gonzalez-Bobes, Francisco,Fenster, Michael D. B.,Kiau, Susanne,Kolla, Laxma,Kolotuchin, Sergei,Soumeillant, Maxime
supporting information; experimental part, p. 813 - 816 (2009/04/21)
The outstanding ability of dirhodium α,α,α′, α′-tetramethyl-1,3-benzenedipropanoate [Rh2(esp) 2; esp=α,α,α′,α′-tetramethyl-1,3- benzene-dipropanoate] to catalyze the cyclopropanation of a wide range of alkenes with malonate-derived carbenoids under mild reaction conditions is reported in this communication. The experimental protocol is remarkably simple, uses readily accessible and stable dimethyl diazomalonate with very low catalyst loading. More importantly, the alkene is employed as a limiting reagent.
