111098-30-7Relevant articles and documents
Conversions of 2-aminopyridines into 5-substituted derivatives mediated by 1-hydroxymethylbenzotriazole
Katritzky, Alan R.,El-Zemity, Saad,Lang, Hengyuan
, p. 3129 - 3134 (2007/10/03)
2-Aminopyridines are benzotriazolylmethylated at the 5-position by 1-hydroxymethylbenzotriazole.The methylene group of 2-amino-5-(benzotriazolylmethyl)pyridines 6 can be mono- or di-lithaited and subsequently substituted by various electrophiles.The benzo
The Chemistry of Benzotriazole. Part 3. The Aminoalkylation of Benzotriazole
Katritzky, Alan R.,Rachwal, Stanislaw,Rachwal, Bogumila
, p. 799 - 804 (2007/10/02)
1-(1-Hydroxyalkyl)benzotriazoles convert a wide variety of aromatic and heteroaromatic primary amines into their mono N- derivatives in high yield.Aliphatic primary amines frequently give bis-derivatives.Product structure is established by 13C n.m.r.; dangers in the use of 1H n.m.r. to distinguish 1- and 2-substituted benzotriazoles are pointed out.