111099-05-9

Upstream product

• 100-52-7 benzaldehyde 
• 51789-57-2 (endo-methyl-2 bicyclo<2.2.1>heptene-5) yl-2 ethyl cetone 
• 51789-57-2 2-methyl endo bicyclo <2.2.1>-5-hepten-2-yl ethyl ketone 
• 39198-49-7 2-methyl-5-norbornene-2-carbonyl chloride 
• 119030-96-5 exo-(hydroxy-1 n-propyl)-5 endo-methyl-5 bicyclo<2.2.1>heptene-2 
• 34618-30-9 endo-bicyclo[2.2.1]hept-5-ene-2-methyl-2-carboxaldehyde 

Downstream Products

• 111099-15-1 syn 4,5 dimethyl-2,4 phenyl-5 trimethylsiloxy-5 pentene-1 one-3 
• 116047-24-6 syn-1,2 syn-2,3 dimethyl-2,4 phenyl-1 pentene-4 diol-1,3 
• 119031-19-5 exo (anti 1,2 syn-2,3 methyl-2 phenyl-3 propanediol-1,3 yl-1)-5 endo methyl-5 bicyclo<2.2.1>heptene-2 

Relevant academic research and scientific papers

ALDOLISATION STEREOCONTROLEE PAR UN GROUPE TERMOLABILE. SYNTHESE STEREOSELECTIVE DE COMPOSES POSSEDANT TROIS CARBONES ASYMMETRIQUES CONSECUTIFS.

The bulkiness of thermolabile norbornenyl and oxanorbornenyl groups has been used to induce good to excellent syn diastereoselective aldol condensations between Diels-Alder adducts of α,β-ethylenic ketones and various aldehydes.The aldols thus obtained gi

STEREOSELECTIVE ALDOL CONDENSATIONS INDUCED BY A THERMOLABILE GROUP.

Diastereoselective aldol condensations between exo, endo and 2-methyl endo bicyclo-5-hepten-2-yl ethyl ketones and aldehydes are achieved via the ketones Z-lithium enolates prepared with lithium hexamethyldisilazide.The aldols thus obtained give rise by a retro Diels-Alder reaction to syn α-methyl-β-siloxy-α'-ethylenic ketones of potential value for polyhydroxylated natural product synthesis.