111102-64-8

Upstream product

• 612-16-8 (2-methoxyphenyl)methanol 
• 20898-43-5 4-(2-tert-butoxycarbonylamino-2-methoxycarbonyl-ethyl)-1H-imidazole-1-carboxylic acid tert-butyl ester 
• 7143-01-3 Methanesulfonic anhydride 
• 4467-54-3 histidine methyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 111102-72-8 3-(2-Methoxybenzyl)-L-histidine dihydrochloride 

Relevant academic research and scientific papers

4,5,6,7-TETRAHYDRO-1H-IMIDAZO(4,5-C)PYRIDINE-6-CARBOXYLIC ACID ANALOGS HAVING ANTIHYPERTENSIVE ACTIVITY

This invention relates to novel substituted derivatives of 4,5, 6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid and analogs thereof, which are useful for the treatment of hypertension, as well as, novel pharmaceutical compositions and methods of use.

Regiospecific Synthesis of 3-Substituted L-Histidines

3-Substituted L-histidine derivatives were prepared by a regiospecific alkylation of N,1-bis-Boc-L-histidine methyl ester with in situ-generated alkyl triflates, benzyl triflates, and benzyl mesylates.Subsequent acid hydrolysis of N-Boc and methyl ester p