111113-67-8Relevant articles and documents
Synthesis and Biological Evaluation of 8-Deazahomofolic Acid and Its Tetrahydro Derivative
DeCraw, J. I.,Colwell, W. T.,Brown, V. H.,Sato, M.,Kisliuk, R. L.,et al.
, p. 150 - 153 (2007/10/02)
The syntheses of 8-deazahomofolic acid and its tetrahydro derivative, potential inhibitors of thymidylate synthase (TS) and other folate related enzymes, are described.Wittig condensation of 2-acetamido-6-formyl-4-pyrimidinol with the triphenylphosphine y