111113-68-9

Upstream product

• 111113-66-7 4-{Acetyl-[(E)-5-(2-acetylamino-6-hydroxy-pyrimidin-4-yl)-3-oxo-pent-4-enyl]-amino}-benzoic acid ethyl ester 
• 111113-65-6 4-{Acetyl-[3-oxo-4-(triphenyl-λ⁵-phosphanylidene)-butyl]-amino}-benzoic acid ethyl ester 
• 60656-63-5 2-acetamido-4-hydroxy-6-formylpyrimidine 
• 100-34-5 benzene diazonium chloride 
• 111113-67-8 1-(2'-acetamido-4'-hydroxy-6'-pyrimidinyl)-5-(N-acetyl-p-carbethoxyanilino)pentan-3-one 

Downstream Products

• 111113-72-5 (S)-2-{4-[[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-yl)-ethyl]-(2,2,2-trifluoro-acetyl)-amino]-benzoylamino}-pentanedioic acid diethyl ester 
• 111113-73-6 8-deazahomopteroic acid 
• 111113-71-4 4-[[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-yl)-ethyl]-(2,2,2-trifluoro-acetyl)-amino]-benzoic acid 
• 111113-70-3 8-deazahomopteroic acid 
• 111113-69-0 ethyl N¹¹-acetyl-8-deazahomopteroate 

Relevant academic research and scientific papers

Synthesis and Biological Evaluation of 8-Deazahomofolic Acid and Its Tetrahydro Derivative

The syntheses of 8-deazahomofolic acid and its tetrahydro derivative, potential inhibitors of thymidylate synthase (TS) and other folate related enzymes, are described.Wittig condensation of 2-acetamido-6-formyl-4-pyrimidinol with the triphenylphosphine y