111114-29-5

Upstream product

• 41070-31-9 4,4-Dimethyl-1-(2,4,6-trimethyl-phenyl)-pentane-1,3-dione 

Downstream Products

• 154613-61-3 4,4-dimethyl-2-mesitylpent-1-ene-1,3-dione 
• 143918-75-6 2,2-Dimethyl-4-(4-methyl-benzoyl)-cyclobutanone 
• 143918-74-5 4,4-Dimethyl-3-oxo-2-p-tolyl-pentanoic acid methyl ester 

Relevant academic research and scientific papers

An improved synthesis of 2-diazo-1,3-diketones

The sodium hydride/dibenzo-18-crown-6 ether system was found to be an effective base for the synthesis of 1,3-diketones by the Claisen condensation. The use of potassium fluoride (with or without crown ether) as the base in diazo-transfer reactions extends this reaction to the synthesis of hindered diazo diketones. In the case of isomeric 1,3-diketones, the stereoselectivity of the process considerably rises.

Investigations on the Conformation of 2-Diazo-1,3-diketones

Conformational analyses of 2-diazo-1,3-diketones (2a-f) with bulky substituents are performed by applying 1H- and 13C-NMR measurements in solution (and in solid state).