1111310-87-2Relevant academic research and scientific papers
Synthesis of isoindoles via 1,3-dipolar cycloaddition of α-azido carbonyl compounds onto intramolecular alkenes and their conversion into substituted aromatic hydrocarbons
Tong, Benny Meng Kiat,Hui, Benjamin Wei-Qiang,Chua, Sze Hui,Chiba, Shunsuke
supporting information; experimental part, p. 3552 - 3562 (2011/12/04)
α-Azido carbonyl compounds bearing a 2-alkenylaryl moiety in the α-position are found to be promising precursors in the synthesis of isoindoles via 1,3-dipolar cycloaddition of azides to alkenes. Applications of these isoindoles in the preparation of 1,2,3,4-tetrasubstituted naphthalene and 9,10-disubstituted anthracene derivatives were developed via [4+2]-cycloaddition reactions of isoindoles with dimethyl acetylenedicarboxylate and benzynes, respectively, followed by deaminative aromatization. Georg Thieme Verlag Stuttgart.
Orthogonal synthesis of isoindole and isoquinoline derivatives from organic azides
Hui, Benjamin Wei-Qiang,Chiba, Shunsuke
supporting information; experimental part, p. 729 - 732 (2009/08/12)
(Chemical Equation Presented) α-Azido carbonyl compounds bearing a 2-alkenylaryl moiety at the α-position are found to be promising precursors for synthesis of isoindole and isoquinoline derivatives via 1,3-dipolar cycloaddrtion of azides onto alkenes and fcrelectrocyclization of N-H imine intermediates, respectively.
