1111646-71-9Relevant academic research and scientific papers
Rearrangement of dialkyl-2-(azetidin-3-yl)propane-1,3-dioates-a structural revision
Faust, Mark R.,Hoesl, Cornelia E.,Wanner, Klaus T.
experimental part, p. 2981 - 2988 (2009/05/31)
The rearrangement reaction of dialkyl 2-[1-diphenylmethyl)azetidin-3-yl]propane-1,3-dioates during saponification was studied. Contrary to a previous report postulating the formation of a 4-(hydroxy-methyl)-2-oxo-pyrrolidine-3-carboxylic acid derivative, our analytical data showed that the rearrangement reaction led to a lactone ring. This structural revision is based on elemental analysis, IR and two-dimensional NMR studies.
