1111662-67-9

Upstream product

• 4368-68-7 1-benzyl-1H-[1,2,3]triazole 
• 106-43-4 para-chlorotoluene 
• 852657-84-2 1-benzyl-4-p-tolyl-1H-[1,2,3]triazole 
• 624-31-7 4-tolyl iodide 

Relevant academic research and scientific papers

Pd-catalyzed ligand-free C(5)–H arylation of 1,4-disubstituted 1,2,3-triazoles promoted by microwaves

Pd(OAc)2-catalyzed regioselective C(5)–H arylation of 1,4-disubstituted 1,2,3-triazoles was achieved without ligand under microwave conditions in 1 h, generating 1,4,5-trisubstituted 1,2,3-triazoles with good to excellent yields. The obtained molecules can be easily converted into 4,5-disubstituted 1,2,3-triazoles through the debenzylation process with one-pot manipulation.

Palladium-catalyzed direct arylations of 1,2,3-triazoles with aryl chlorides using conventional heating

Generally applicable, palladium-catalyzed direct arylations of 1,2,3-triazoles with aryl chlorides were accomplished through conventional heating at reaction temperatures of 105-120°C. Thereby, intra- and intermolecular C-H bond functionalizations were achieved with a variety of differently substituted chlorides as electrophiles, bearing numerous valuable functional groups.