852657-84-2

Upstream product

• 100-39-0 benzyl bromide 
• 766-97-2 4-n-methylphenylacetylene 
• 100-44-7 benzyl chloride 
• 104-09-6 4-methylphenylacetaldehyde 
• 622-79-7 benzyl azide 
• 1312680-84-4 1-(methylsulfonyl)-4-(p-tolyl)-1H-1,2,3-triazole 
• 75-52-5 nitromethane 
• 104-87-0 4-methyl-benzaldehyde 
• 2227-58-9 3-(4-methylphenyl)prop-2-ynoic acid 
• 52999-17-4 lithium (p-tolyl)acetylide 
• 861805-80-3 diphenyl(p-tolylethynyl)stibane 
• 73839-44-8 (Z)-1-[2-bromovinyl]-4-methylbenzene 
• 33675-56-8 1-(iodoethynyl)-4-methylbenzene 
• 60672-33-5 4-methyl-N'-(1-(p-tolyl)ethylidene)benzenesulfonohydrazide 

Downstream Products

• 1220349-70-1 (E)-1-benzyl-5-styryl-4-p-tolyl-1H-1,2,3-triazole 
• 1220349-64-3 (E)-methyl 3-(3-benzyl-5-p-tolyl-3H-1,2,3-triazol-4-yl)acrylate 
• 1043420-03-6 1-benzyl-4-(4-tolyl)-5-phenyl-1H-1,2,3-triazole 

Relevant academic research and scientific papers

Determining the Origin of Rate-Independent Chemoselectivity in CuAAC Reactions: An Alkyne-Specific Shift in Rate-Determining Step

We report a kinetic and spectroscopic analysis of alkyne-dependent chemoselectivity in the copper-catalyzed azide–alkyne click (CuAAC) reaction. Studies of six alkyne subtypes reveal that the rate-determining step (RDS) of an aromatic ynamine class is shi

Synthesis of 5-organostibano-1H-1,2,3-triazoles by Cu-catalyzed azide-alkyne cycloaddition and their application in the acyl-induced deantimonation for the preparation of fully substituted 5-acyl-1,2,3-triazoles

The Cu-catalyzed azide-alkyne cycloaddition by the reaction of various ethynylstibanes with benzylazide in the presence of CuBr (5?mol%) under aerobic conditions led to the formation of trisubstituted 5-organostibano-1H-1,2,3-triazoles. Further, the acyl-induced deantimonation of 5-stibanotriazoles with acyl chlorides in the presence of N,N-dimethyl-4-aminopyridine and triethylamine afforded the corresponding trisubstituted 5-acyltriazoles in moderate-to-good yields.

Base-Induced Highly Regioselective Synthesis of N2-Substituted 1,2,3-Triazoles under Mild Conditions in Air

We developed a highly regioselective base-induced synthesis of N2-substituted 1,2,3-triazoles from N-sulfonyl-1,2,3-triazoles and alkyl bromides/alkyl iodides at room temperature. We propose an SN2-like mechanistic pathway to explain the high N2-regioselectivity. The protocol features a broad substrate scope and generates products in good to excellent yields (72–90%).

CuO–NiO bimetallic nanoparticles supported on graphitic carbon nitride with enhanced catalytic performance for the synthesis of 1,2,3-triazoles, bis-1,2,3-triazoles, and tetrazoles in parts per million level

The unification of CuCl2·2H2O and NiCl2·6H2O with the support of graphitic carbon nitride yielded to form an efficient, synergistic, bimetallic nano-catalyst CuO–NiO@g-C3N4. FT-IR, SEM, TEM

Highly Efficient and Stable Atomically Dispersed Cu Catalyst for Azide-Alkyne Cycloaddition Reaction

In this study, we report a highly stable and efficient single-atom Cu dispersed on N-doped porous carbon as a superior catalyst for azide-alkyne cycloaddition reaction. A broad set of 1,4-disubstituted 1,2,3-triazoles was synthesized in high to excellent

A new amido-phosphane as ligand for copper and silver complexes. Synthesis, characterization and catalytic application for azide-alkyne cycloaddition in glycerol

The new sterically hindered amido-phosphane 1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane-3,7-diylbis(phenylmethanone), DBPTA (1), has been obtained via an open-cage double N-acylation of 1,3,5-triaza-7-phosphadamantane (PTA) using benzoic anhydride. DBPTA i

Self-assembly of cuprous iodide cluster-based calix[4]resorcinarenes and photocatalytic properties

The controlled self-assembly of cuprous iodide cluster-based supramolecular architectures with a tunable structure is still a big challenge to date. We adopt a conformation-adaptive self-assembly strategy to precisely construct two [CumIn

Copper(I)-chitin biopolymer based: An efficient and recyclable catalyst for click azide–alkyne cycloaddition reactions in water

The naturally occurring α-chitin biopolymer was employed for the immobilisation of copper(I) ion, resulting into a new bioconjugate complex, namely, Cu(I)-α-chitin (CuI-CHT) with catalytic efficiency in copper-catalysed azide–alkyne cycloaddition reaction

Construction of Stable Metal–Organic Framework Platforms Embedding N-Heterocyclic Carbene Metal Complexes for Selective Catalysis

We report a bottom-up approach to immobilize catalysts into MOFs, including copper halides and gold chloride in a predictable manner. Interestingly, the structures of MOFs bearing NHC metal complexes maintained a similar 4-fold interpenetrated cube. They

Synthesis of copper containing polyaniline composites through interfacial polymerisation: An effective catalyst for Click reaction at room temperature

Polyaniline (PANI) supported Cu (Cu/PANI) catalyst served as an efficient heterogeneous catalyst for the regioselective synthesis of 1,4-disubstituted-1H-1,2,3-triazoles via click chemistry approach. Herein, we have illustrated the development of two copp