1111872-03-7

Basic information

• Product Name: 8-(4-chlorophenyl)-1H,5H-tetrazolo[1,5-a]pyrido[2,3-d]pyrimidin-5-one
• Synonyms: 8-(4-chlorophenyl)-1H,5H-tetrazolo[1,5-a]pyrido[2,3-d]pyrimidin-5-one
• CAS NO: 1111872-03-7
• Molecular Weight: 374.789
• Mol File: 1111872-03-7.mol

Chemical Properties

• CAS DataBase Reference: 8-(4-chlorophenyl)-1H,5H-tetrazolo[1,5-a]pyrido[2,3-d]pyrimidin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(4-chlorophenyl)-1H,5H-tetrazolo[1,5-a]pyrido[2,3-d]pyrimidin-5-one(1111872-03-7)
• EPA Substance Registry System: 8-(4-chlorophenyl)-1H,5H-tetrazolo[1,5-a]pyrido[2,3-d]pyrimidin-5-one(1111872-03-7)

Safety Data

• Hazardous Substances Data: 1111872-03-7(Hazardous Substances Data)

Upstream product

• 494190-05-5 2-hydrazino-5-phenyl-7-(4-chlorophenyl)-3H,4H-pyrido[2,3-d]pyrimidin-4(4H)-one 

Downstream Products

• 1042092-97-6 2-amino-5-phenyl-7-(4-chlorophenyl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Synthesis and reactions of some novel triazolo-, azolo-, tetrazolo-pyridopyrimidine and their nucleoside derivatives

Pyridopyrimidine reacted with aromatic aldehydes afforded the arylhydrazone 2a,b which could be cyclized into the pyrido[2,3-d][1,2,4]triazolo[4,3-a] pyrimidine 3a,b, with formic acid, and carbon disulphide to give pyrido[2,3-d][1,2,4]traizolo[4,3-a]pyrimidine 4, 5. Reaction of 1 with nitrous acid afforded tetrazolo[1,5-a]pyrido[2,3-d]pyrimidine 6, which was reduced by zinc dust to give 2-amino-pyrido-[2,3-d]pyrimidine 7. Finally the reaction of 2-hydrazino 1 with D-xylose or D-glucose afforded the acyclic N-nucleoside 8, 11 which were converted into tetra/penta O-acetate acyclic C-nucleoside 9, 12 in acetic anhydride/pyridine. De-acetylation of compounds 9, 12 afforded C-nucleosides 10, 13.