111193-66-9

Upstream product

• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 405215-53-4 N-benzyloxycarbonyl-2,5-dideoxy-2,5-imino-3,4-O-isopropylidene-L-ribose 
• 111193-62-5 (2S,3R,4S)-N-benzyloxycarbonyl-3,4-dihydroxyproline-3,4-isopropylidene acetal methyl ester 
• 111193-60-3 (S)-3,4-Dihydroxy-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 5211-24-5 (2S)-2,5-dihydro-1H-pyrrole-1,2-dicarboxylic acid 2-methyl 1-(phenylmethyl) ester 
• 111265-96-4 (2R,3R,4S)-1-(benzyloxycarbonyl)-2-(hydroxymethyl)pyrrolidine-3,4-diol 3,4-O-isopropylidene acetal 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 111193-68-1 (3aR,4S,6aS)-2,2-Dimethyl-4-methylsulfanylmethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid benzyl ester 
• 1632124-95-8 (2R,3R,4S)-N-benzyloxycarbonyl-2-azidomethyl-3,4-O-isopropylidene-pyrrolidine-3,4-diol 
• 1632125-08-6 C₃₀H₄₆N₄O₄ 
• 111193-67-0 (3aR,4S,6aS)-4-((S)-3-Amino-3-carboxy-propylsulfanylmethyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives

A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for their ability to inhibit the growth of pancreatic ductal adenocarcinoma cells in vitro. The new compounds are shown to exhibit anticancer activity at concentrations in the μM range. ARKAT-USA, Inc.