111197-85-4

Upstream product

• 111197-80-9 (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-butanone 
• 149-73-5 trimethyl orthoformate 
• 111199-07-6 (S)-2-hydroxy-3,N,N-trimethylbutanamide 
• 24347-63-5 methyl (S)-2-hydroxy-3-methylbutanoate 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 72-18-4 L-valine 

Downstream Products

• 111197-90-1 (S)-2-methylsulfonyloxy-1-(4-methoxyphenyl)-3-methyl-1-butanone dimethyl acetal 

Relevant academic research and scientific papers

A General Synthetic Method of Chiral 2-Arylalkanoic Esters via Thermal 1,2-Rearrangement

(S)-1-Aryl-2-sulfonyloxy-1-alkanone acetals, prepared from natural ethyl (S)-lactate or (S)-valine (chiral sources) by the use of a Grignard reaction, were rearranged under hydrolytic conditions in the presence of a base to give (S)-2-arylalkanoic esters which in general, showed much higher pharmacological activities than their antipodes.