111197-88-7Relevant articles and documents
A General Synthetic Method of Chiral 2-Arylalkanoic Esters via Thermal 1,2-Rearrangement
Honda, Yutaka,Ori, Aiichiro,Tsuchihashi, Gen-ichi
, p. 1027 - 1036 (2007/10/02)
(S)-1-Aryl-2-sulfonyloxy-1-alkanone acetals, prepared from natural ethyl (S)-lactate or (S)-valine (chiral sources) by the use of a Grignard reaction, were rearranged under hydrolytic conditions in the presence of a base to give (S)-2-arylalkanoic esters which in general, showed much higher pharmacological activities than their antipodes.