(8S-cis)-8-Acetyl-10-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione is a tert-butyldiphenylsilyl protected degradation product of Doxorubicin (D194500), an anthracycline antibiotic.
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Basic information
- Product Name: (8S-cis)-8-Acetyl-10-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione
- Synonyms: (8S-cis)-8-Acetyl-10-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione
- CAS NO:111248-01-2
- Molecular Formula: C27H32O8Si
- Molecular Weight: 512.62368
- EINECS: N/A
- Product Categories: Carbohydrates & Derivatives, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File: 111248-01-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Refrigerator, under inert atmosphere
- Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
- CAS DataBase Reference: (8S-cis)-8-Acetyl-10-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione(CAS DataBase Reference)
- NIST Chemistry Reference: (8S-cis)-8-Acetyl-10-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione(111248-01-2)
- EPA Substance Registry System: (8S-cis)-8-Acetyl-10-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione(111248-01-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 111248-01-2(Hazardous Substances Data)
111248-01-2 Usage
Uses
Used in Pharmaceutical Industry:(8S-cis)-8-Acetyl-10-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione is used as a protected degradation product for [application reason]. The tert-butyldiphenylsilyl protection allows for the stabilization and modification of Doxorubicin, potentially enhancing its therapeutic properties and reducing side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 111248-01-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,2,4 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 111248-01:
(8*1)+(7*1)+(6*1)+(5*2)+(4*4)+(3*8)+(2*0)+(1*1)=72
72 % 10 = 2
So 111248-01-2 is a valid CAS Registry Number.
111248-01-2Upstream product
111248-01-2Downstream Products
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(8S-cis)-8-Acetyl-10-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione
